Gene

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

1. NG_051195.1 RefSeqGene

   Range 5190..19041 Download GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. NM_001177547.3 → NP_001171018.1 sialic acid-binding Ig-like lectin 6 isoform 4

   Status: REVIEWED

   Description Transcript Variant: This variant (4) uses an alternate, in-frame splice site and lacks an alternate in-frame exon in the 5′ coding region, compared to variant 1. This results in a shorter protein (isoform 4), compared to isoform 1. Source sequence(s) AC020914, AK300170, BC035359 Consensus CDS CCDS54307.1 UniProtKB/Swiss-Prot O43699 Related ENSP00000410679.1, ENST00000436458.5 Conserved Domains (3) summary pfam07679Location:202 → 284 I-set; Immunoglobulin I-set domain pfam13927Location:111 → 182 Ig_3; Immunoglobulin domain cl11960Location:28 → 105 Ig; Immunoglobulin domain

2. NM_001177548.3 → NP_001171019.1 sialic acid-binding Ig-like lectin 6 isoform 5 precursor

   Status: REVIEWED

   Description Transcript Variant: This variant (5) uses an alternate, in-frame splice site and lacks an exon in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (5) is shorter and has a distinct C-terminus, compared to isoform 1. Source sequence(s) AC020914, AK300182, BC035359 Consensus CDS CCDS54308.1 UniProtKB/Swiss-Prot O43699 Related ENSP00000353071.4, ENST00000359982.8 Conserved Domains (4) summary smart00410Location:36 → 141 IG_like; Immunoglobulin like pfam07679Location:265 → 347 I-set; Immunoglobulin I-set domain pfam13927Location:147 → 218 Ig_3; Immunoglobulin domain cl11960Location:31 → 141 Ig; Immunoglobulin domain

3. NM_001177549.3 → NP_001171020.1 sialic acid-binding Ig-like lectin 6 isoform 6 precursor

   Status: REVIEWED

   Description Transcript Variant: This variant (6) uses an alternate, in-frame splice site and lacks two exons in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (5) is shorter and has a distinct C-terminus, compared to isoform 1. Source sequence(s) AC020914, BC035359, BC140798, D86359 Consensus CDS CCDS59417.1 UniProtKB/Swiss-Prot O43699 Related ENSP00000375674.3, ENST00000391797.3 Conserved Domains (4) summary smart00410Location:36 → 141 IG_like; Immunoglobulin like pfam07679Location:243 → 325 I-set; Immunoglobulin I-set domain pfam13927Location:143 → 207 Ig_3; Immunoglobulin domain cl11960Location:31 → 141 Ig; Immunoglobulin domain

4. NM_001245.7 → NP_001236.4 sialic acid-binding Ig-like lectin 6 isoform 1 precursor

   See identical proteins and their annotated locations for NP_001236.4

   Status: REVIEWED

   Description Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Source sequence(s) AC020914, BC035359 Consensus CDS CCDS12834.3 UniProtKB/Swiss-Prot A8MV71, B2RTS8, C9JBE5, F8WA78, O15388, O43699, O43700 Related ENSP00000401502.2, ENST00000425629.8 Conserved Domains (4) summary smart00410Location:36 → 141 IG_like; Immunoglobulin like pfam07679Location:254 → 336 I-set; Immunoglobulin I-set domain pfam13927Location:147 → 218 Ig_3; Immunoglobulin domain cl11960Location:31 → 141 Ig; Immunoglobulin domain

5. NM_198845.6 → NP_942142.3 sialic acid-binding Ig-like lectin 6 isoform 2 precursor

   Status: REVIEWED

   Description Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5′ coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Source sequence(s) AC020914, BC035359 Consensus CDS CCDS12835.3 UniProtKB/Swiss-Prot O43699 Related ENSP00000344064.4, ENST00000346477.7 Conserved Domains (4) summary smart00410Location:36 → 141 IG_like; Immunoglobulin like pfam07679Location:238 → 320 I-set; Immunoglobulin I-set domain pfam13927Location:147 → 218 Ig_3; Immunoglobulin domain cl11960Location:31 → 141 Ig; Immunoglobulin domain

6. NM_198846.6 → NP_942143.3 sialic acid-binding Ig-like lectin 6 isoform 3 precursor

   See identical proteins and their annotated locations for NP_942143.3

   Status: REVIEWED

   Description Transcript Variant: This variant (3) lacks two exons in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1. Source sequence(s) AC020914, BC035359, D86359 Consensus CDS CCDS12836.3 UniProtKB/Swiss-Prot O43699 Related ENSP00000345907.4, ENST00000343300.8 Conserved Domains (4) summary smart00410Location:36 → 141 IG_like; Immunoglobulin like pfam07679Location:254 → 336 I-set; Immunoglobulin I-set domain pfam13927Location:147 → 218 Ig_3; Immunoglobulin domain cl11960Location:31 → 141 Ig; Immunoglobulin domain